Researchers have created the first interactive map showing the actions of the proteins that govern the process of cell division, a process known as mitosis.
The map, published in the journal Nature, builds on a 2010 study by scientists at the European Molecular Biology Laboratory (EMBL) – a research institute comprising specialists from 25 countries, with facilities in Germany, Spain, Italy and France – which identified which parts of the human genome are required for a human cell to divide.
The latest work, by the same team, drills down to another level. Cells don’t run on genomic DNA, but on the proteins encoded by it. The map tracks five of the proteins critical to the process of mitosis.
“Until now, individual labs have mostly been looking at single proteins in living cells,” says EMBL’s Jan Ellenberg.
“Supported by the follow-up European Union project MitoSys we were now able to take a systems approach, and look at the bigger picture by studying the dynamic networks many proteins form in living human cells.”
Originally published by Cosmos as The proteins that pull your cells apart
Cosmos
Curated content from the editorial staff at Cosmos Magazine.
Read science facts, not fiction...
There’s never been a more important time to explain the facts, cherish evidence-based knowledge and to showcase the latest scientific, technological and engineering breakthroughs. Cosmos is published by The Royal Institution of Australia, a charity dedicated to connecting people with the world of science. Financial contributions, however big or small, help us provide access to trusted science information at a time when the world needs it most. Please support us by making a donation or purchasing a subscription today.
