This is an extreme close-up of a protein called Hsp104, found in a fungus called Calcarisporiella Thermophila. The extraordinarily detailed image is the result of a combination of X-ray crystallography and cryo-electron microscopy (cryo-EM), developed by researchers at the US Department of Energy’s Argonne National Laboratory, in Illinois.
Hsp104 is a type of protein known as a chaperone, because it assists other proteins to fold correctly, and can also repair those are malformed. It is thought that chaperones have potential to be adapted to fight the onset of neurodegenerative diseases, such as Parkinson’s.
Details of the research are published in the journal Structure.
Originally published by Cosmos as A protein chaperone
Cosmos
Curated content from the editorial staff at Cosmos Magazine.
Read science facts, not fiction...
There’s never been a more important time to explain the facts, cherish evidence-based knowledge and to showcase the latest scientific, technological and engineering breakthroughs. Cosmos is published by The Royal Institution of Australia, a charity dedicated to connecting people with the world of science. Financial contributions, however big or small, help us provide access to trusted science information at a time when the world needs it most. Please support us by making a donation or purchasing a subscription today.